Augmenting Quality of Life

Detector Options: FID, MS

Detector Options: FID, MS

Using Ion chromatography we are able to separates ions and polar molecules based on their affinity to the ion exchanger. It works on almost any kind of charged molecule—including large proteins, small nucleotides, amino acids and etc.

Using polarimetry we are capable of  analyzing chiral substances and determine their concentration in solutions. Fields of application are quality control, laboratory analytics, as well as in R&D in the pharmaceutical, cosmetics, chemical, food, and medical industries. 

UV/Vis spectroscopy is routinely used for the quantitative determination of different analytes, such as transition metal ions, highly conjugated organic compounds, and biological macromolecules. 

We provides manufacturing support by offering cleanliness testing services such as. Determining size and distribution of particulates on precision manufactured devices, particle size in colloidal solutions and inks, size and distribution of particles in critical fluids such as Hydraulic fluids and Combustion fluids.

Karl Fischer titration is a classic titration method in chemical analysis that uses coulometric or volumetric titration to determine trace amounts of water in a sample. It was invented in 1935 by the German chemist Karl Fischer. Here at MPP we still use the original method, however the titration is done with an automated Karl Fischer titrator.

Complexometric, Redox and Potentiometric.

Inductively coupled plasma mass spectrometry is a type of mass spectrometry that uses an Inductively coupled plasma to ionize the sample. It atomizes the sample and creates atomic and small polyatomic ions, which are then detected.

The LC-ICP-MS is a powerful tool for the detection of residual chemical compounds, confirmatory identification of small organic molecules, and confirmation and quantitation of contaminants and adulterants in pharmaceutical and food samples.

IR (Infrared) Spectroscopy is the analysis of infrared light interacting with a molecule. This can be analyzed in three ways by measuring absorption, emission and reflection. The main use of this technique is in organic and inorganic chemistry. here at MPP our chemists use this procedure to  determine functional groups in molecules.

One common GMP testing we perform, is pH and Conductivity.
pH ‘power of hydrogen’ is used to determine whether a solution is acidic or basic and how acidic or basic the solution is. Conductivity however, is the amount of electricity a substance of unit mass and area allows to pass through it.

This GMP testingt is used to define the weight or density of a liquid as compared to the density of an equal volume of water at a specified temperature. The temperature used for measurement is usually 39.2o F (4o C), because this temperature allows water to assume its maximum density.

This GMP testing is a widely used test method to determine the moisture content of a sample, although occasionally it may refer to the loss of any volatile matter from the sample. Loss on drying does not usually refer to molecularly bound water or water of crystallisation.

This GMP test utilizes a procedure to measure the amount of residual substance not volatilized from a sample when the sample is ignited in the presence of sulfuric acid according to the procedure described below. This test is usually used for determining the content of inorganic impurities in an organic substance

The GMP Melting points test is used to characterize organic and inorganic crystalline compounds and to ascertain their purity. Pure substances melt at a sharp, highly-defined temperature (very small temperature range of 0.5 – 1 °C) whereas impure, contaminated substances generally exhibit a large melting interval.

Photostability of a drug substance may be defined as the response of the drug or drug product to the exposure to solar, UV, and visible light in the solid, semisolid, or liquid state that leads to a physical or chemical change.

Wet chemistry/bench chemistry uses classical methods such as observation to analyze materials. It is called wet chemistry since most analyzing is done in the liquid phase. 

Refractive index can be used to identify an unknown liquid compound, or it can be used as a means of measuring the purity of a liquid compound by comparing it to literature values. The closer the refractive index is to the literature values, the purer the sample.

Many of today’s biopharmaceutical formulations may potentially suffer from oxidation to some degree. MPP’s headspace method demonstrates how ability to quickly and accurately determine headspace oxygen levels saves time and enables deep insight into formulation stability

Osmolality measurements are carried out to establish the isotonicity of intravenous solutions, injections, nasal and eye drops. Preparations which are hypertonic or hypotonic can cause severe irritation when injected into the bloodstream, tissue or when applied to mucous membranes like cornea and wounds. This is a routine test for all our injectable drug products.